Redox Signaling

One of the core technology of KnoWhereBio is redox biochemistry. In intracellular signaling, the effect of signal transmission depends on the redox state. KnoWhereBio is applying molecular modeling technology to control this redox state in the new drug development as used in BETi. 

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Regulatory: e.g. Kinases (EGFR), Keap1, & PKM2 (CYS797); EGFR kinase domain NS-062 5Y25